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Fig. 2 | Genome Medicine

Fig. 2

From: Cord blood DNA methylome in newborns later diagnosed with autism spectrum disorder reflects early dysregulation of neurodevelopmental and X-linked genes

Fig. 2

ASD DMR genes are significantly enriched for X-linked and synaptic genes in males and females. Terms significantly enriched among cord blood ASD DMR genes in both discovery and replication sample sets for either males or females (*q < 0.05). Heatmaps show −log10(q-value) for enrichment in genes annotated to DMRs relative to genes annotated to background calculated using the Database for Annotation, Visualization, and Integrated Discovery (DAVID) for a all categories except tissue expression or b tissue expression categories only. Both heatmaps were plotted using the same scale and terms were sorted by replicated sex (pooled males TD n = 56, ASD n = 56; pooled females TD n = 20, ASD n = 20)

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