Table 2 Emergence of main MDR genome clusters and association with putative compensatory mutations
gCL (N isolates) | Lineage | Cluster age [years] (95% HPD) | Isolates with putative compensatory mutation |
|---|---|---|---|
1 (8) | EAI | 15.8 (9.7–22.3) | 0 (0%) |
3 (28) | X-type | 20.5 (13.6–24.5) | 28 (100%) |
6 (7) | EAI | 16.5 (11.2–22.7) | 7 (100%) |
8 (5) | Beijing | 7.8 (4.7–11.3) | 2 (40.0%) |
9 (4) | S-type | 6.9 (3.5–11.2) | 0 (0%) |
10 (40) | S-type | 17.2 (12.4–22.6) | 33 (82.5%) |
12 (3) | Haarlem | 7.3 (3.0–12.4) | 3 (100%) |
16 (6) | Swaziland H37Rv like | 10.8 (6.6–15.4) | 3 (50.0%) |
19 (3) | X-type | 12.8 (5.0–18.3) | 3 (100%) |
21 (3)1 | X-type | 18.4 (11.4–22.3) | 0 (0%) |
30 (4) | X-type | 7.2 (3.0–8.4) | 0 (0%) |