|
Location
|
Adj.P
|
DeltaM
|
Probes/DMR
|
2D-KS_p value
|
SNPprobes
|
Cross-reactive probes
|
Genes
|
Probes/gene
|
|---|
|
chr10:134150449-134150761
|
2.4E−15
|
− 0.082275
|
8
|
5E−21
|
0
|
0
|
LRRC27
|
81
|
|
chr6:49681176-49681392
|
6.1E−11
|
0.101266
|
8
|
1.3E−16
|
0
|
0
|
CRISP2
|
14
|
|
chr17:33759510-33760309
|
0.0000054
|
0.083168
|
12
|
1.1E−11
|
0
|
0
|
SLFN12
|
22
|
|
chr13:21919004-21919171
|
0.000038
|
− 0.090555
|
3
|
7.9E−11
|
0
|
3
|
LINC00539
|
39
|
|
chr19:57742110-57742424
|
0.005
|
0.05827
|
9
|
0.000000011
|
0
|
0
|
AURKC
|
16
|
|
chr6:30039130-30039802
|
0.0077
|
− 0.114807
|
18
|
0.000000016
|
3
|
0
|
RNF39
|
83
|
|
chr12:311645-313379
|
0.0082
|
0.126218
|
9
|
0.000000017
|
1
|
0
|
RP11-283I3.2, SLC6A12
|
9.59
|
|
chr20:61371016-61371809
|
0.024
|
− 0.041995
|
5
|
0.000000051
|
3
|
0
|
NTSR1
|
38
|
- Differentially methylated DMRs between responders and non-responders to lifestyle intervention; including all datasets at baseline and post-intervention. Top candidate DMRs with adj. P ≤ 0.05. DeltaM represents the difference of the mean average methylation rates between responders and non-responder as computed by metilene. The 2D-KS p value represents a two-dimensional variety of the Kolmogorov-Smirnov test used by metilene. Probes/DMR represents the number of probes within a DMR. SNPprobes represent probes containing a SNP with a frequency > 0.01. Cross-reactive probes indicate potential off-target probe binding. Genes is a comma-separated list of the genes cis to the DMR, and probes/gene is the total number of probes that are cis to the respective genes. Chromosomal location was annotated to genome assembly GRCh37 (hg19)
