Fig. 6

Dual functional effects of individual HSPs among cancer hallmarks. a Association between HSPs and eight cancer hallmarks. Red and blue bars in the outer rings denote the number of cancer types with positive and negative associations. The colored rectangles in the middle denote HSP families. The colored sections of the inner ring denote the cancer hallmarks. b HSPs positively associated with ≥ 5 cancer hallmarks across cancer types. c HSPs negatively associated with ≥ 5 cancer hallmarks across cancer types. The thickness of the curve denotes the number of cancer types with associations between HSPs and cancer hallmarks in b and c