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Fig. 4 | Genome Medicine

Fig. 4

From: Integrated analysis of microbiome and host transcriptome reveals correlations between gut microbiota and clinical outcomes in HBV-related hepatocellular carcinoma

Fig. 4

Functional annotations and pathway analysis of the microbe-associated genes. a Integrated analysis of key microbe-associated genes: functionalannotation and log2FC value of gene from each patient (n = 32, left panel), DFS (based on GEPIA, middle panel), and OS (based on GEPIA, right panel). The red line denotes the average values. Heatmaps represent the log10 (hazard ratio) value of each gene in each kind of tumor. The dark square box denotes that the clinical prognosis was statistically significant. b The GO enrichment analysis based on Metascape. c Pathway analysis based on DAVID 6.8. d Pairwise gene expression correlation analysis using the Pearson method shows interdependent relationships and gene co-expression according to GEPIA. LIHC, Hepatocellular carcinoma; CHOL, Cholangial carcinoma; PAAD, Pancreatic adenocarcinoma; COAD, Colon adenocarcinoma; READ, Rectum adenocarcinoma

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Genome Medicine

ISSN: 1756-994X

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