Table 1 Associations between module M35 and six selected clinical traits in multivariate regression models where adjusting for the other five variables
|  | Basic model (DV ~ M35 + age + sex + study centre + RNAseq technical variables) | Basic model + other 5 variables | ||||
|---|---|---|---|---|---|---|
Dependent variable (DV) | Beta | s.e. | P | Beta | s.e. | P |
Basal insulin secretion rate | 10.75 | 0.95 | 6.83 × 10−29 | 1.92 | 0.50 | 1.23 × 10−04 |
Matsuda insulin sensitivity index | −9.20 | 0.96 | 1.67 × 10−21 | 0.55 | 0.51 | 0.28 |
Triglycerides | 10.06 | 0.96 | 4.67 × 10−25 | 5.01 | 0.89 | 2.17 × 10−08 |
Body mass index | 7.24 | 0.98 | 1.60 × 10−13 | 0.40 | 0.85 | 0.63 |
hsCRP | 7.68 | 0.96 | 2.42 × 10−15 | 5.06 | 0.96 | 1.53 × 10−07 |
Total GLP-1 | 6.40 | 0.96 | 2.99 × 10−11 | 1.94 | 0.91 | 0.03 |