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Table 2 Frequency of defective viral genomes detections

From: Analysis of an Ebola virus disease survivor whose host and viral markers were predictive of death indicates the effectiveness of medical countermeasures and supportive care

 

Total DI reads

5′ DVGs

3′ DVGs

DVGs with deletion

DVGs with insertion

Day 1

83

8 (9.4%)

1 (1.2%)

28 (33.73%)

46 (55.42%)

Day 4

4096

3163 (77.22%)

815 (19.90%)

24 (0.59%)

94 (2.29%)

Day 5

68,219

55,389 (81.19%)

10,926 (16.02%)

447 (0.66%)

1457 (2.14%)

Day 6

109,650

96,162 (87.70%)

11,518 (10.50%)

498 (0.45%)

1472 (1.34%)

Day 7

90,244

71,070 (78.75%)

17,882 (19.82%)

433 (0.48%)

859 (0.95%)

Day 8

76,582

59,710 (77.97%)

16,004 (20.90%)

325 (0.42%)

543 (0.71%)

Day 9

13,202

10,145 (76.84%)

2904 (22.00%)

55 (0.42%)

98 (0.74%)

Day 10

7449

5346 (71.77%)

2074 (27.84%)

17 (0.23%)

12 (0.16%)

Day 11

2179

1678 (77.01%)

471 (21.62%)

14 (0.64%)

16 (0.73%)

Day 12

2914

2125 (72.92%)

762 (26.15%)

10 (0.34%)

17 (0.58%)

Plasma-081015

16

4 (25.00%)

11 (68.75%)

0 (0.00%)

1 (6.25%)

CSF-071015

437

154 (35.24%)

197 (45.08%)

22 (5.03%)

64 (14.65%)

CSF-081015

463

137 (29.59%)

215 (46.44%)

33 (7.13%)

78 (16.85%)