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Fig. 3 | Genome Medicine

Fig. 3

From: An integrated in silico immuno-genetic analytical platform provides insights into COVID-19 serological and vaccine targets

Fig. 3

Mapping of HLA-I A and B epitopes to the spike, nucleocapsid and orf3a protein sequences. Epitopes were inferred using NetMHCpan 4.1. Only strong binding epitopes were selected for analysis, based on the tool’s internal classification system. A representative set of HLA-I alleles were used as described in Grifoni et al. [14]. Binding affinity is based on predicted IC50 values (nM) (a lower concentration equates to a stronger affinity). Shaded region (denoted by A) indicates the spike receptor-binding domain (RBD)

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Genome Medicine

ISSN: 1756-994X

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