Fig. 6
From: 5′-tRF-GlyGCC: a tRNA-derived small RNA as a novel biomarker for colorectal cancer diagnosis
Xenografted CRC tumors increased levels of 5′-tRF-GlyGCC in plasma of mice. a Levels of 5′-tRF-GlyGCC in plasma of nude mice of control (n = 6) or bearing human CRC HCT116 tumor (n = 6). b Relative mRNA level of ALKBH3 in nude mice blood of control (n = 6) or bearing human CRC HCT116 tumor (n = 6). c Levels of 5′-tRF-GlyGCC in plasma of BALB/c mice of control (n = 6) or bearing mouse CRC CT26 tumor (n = 6). d Relative mRNA level of ALKBH3 in BALB/c mice blood control (n = 6) or bearing mouse CRC CT26 tumor (n = 6). e The Spearman correlation between the levels of 5′-tRF-GlyGCC and the mRNA expression of ALKBH3 in xenografted mice. *p < 0.05 as compared with the PBS group