Fig. 4
From: Improved prediction of fracture risk leveraging a genome-wide polygenic risk score
Comparison of the predictive performance of FRAX-CRF, FRAX-BMD, and FRAX-gSOS. a Receiver operating characteristic curves, b precision-recall curves, and c summaries of the predictive performance of FRAX-based scores for predicting incident major osteoporotic fracture risk. d Receiver operating characteristic curves, e precision-recall curves, and f summaries of the predictive performance of FRAX-based scores for predicting incident hip fracture risk. AUROC and AUPRC were derived based on all 90,172 individuals from four cohorts. C-indices were derived based on 4663 men from the MrOS US and 3615 women from the SOF cohorts using Cox proportional hazard models. All CIs were derived from 200 bootstrap replicates