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Fig. 2 | Genome Medicine

Fig. 2

From: Microbiota restoration reduces antibiotic-resistant bacteria gut colonization in patients with recurrent Clostridioides difficile infection from the open-label PUNCH CD study

Fig. 2

Microbiota composition similarity to the donor at 7 days is predictive of treatment outcome. The donor and recipient microbiota compositions were assessed via 16S rRNA gene sequencing followed by DADA2, and their similarity to the donor product was quantified by weighted UniFrac at each timepoint. a Gray lines represent individuals successfully treated with one administration (SI group) while red lines are patients who needed further treatment (RI group, a second product or antibiotics). N = 28 patients and 130 samples. b Plot demonstrating average distance from the donor at timepoints 0 and 7 days after treatment. N = 28 total patients and 44 samples. Box subsumes 75% of the data with a horizontal bar at the median. *p < 0.05, Mann-Whitney U test

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Genome Medicine

ISSN: 1756-994X

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