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Fig. 1 | Genome Medicine

Fig. 1

From: Intra-host variation and evolutionary dynamics of SARS-CoV-2 populations in COVID-19 patients

Fig. 1

Sequence data from various sample types of patients with COVID-19. a SARS-CoV-2 RPM of metatranscriptomic data plotted against RT-qPCR cycle threshold (Ct) value for the clinical samples. b Frequency distribution of samples based on SARS-CoV-2 reads per million (SARS-CoV-2 RPM). c Maximum likelihood tree of consensus SARS-CoV-2 genomes using IQ-TREE. Colors of dotted tips represent the geographic locations of samples. Nucleotide mutations that define the branch were labeled outside the tree. d Distribution of consensus variants (in round circles) detected in the GZMU cohort across the SARS-CoV-2 genome. Colors represent the biological effect of mutations. Non-synonymous variants are denoted by green, synonymous variants by red, and frameshift by blue. EPI_ISL_402125 was used as the reference sequence

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