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Table 1 Differences in phenotypic traits in Danish and Indian cohorts

From: Trans-ethnic gut microbial signatures of prediabetic subjects from India and Denmark

Parameter

Median (and IQR) value in Danish samples

Median (and IQR) value in Indian samples

Wilcoxon test p value

(after BH correction)

NG

PD

NG

PD

NG vs PD (Denmark)

NG vs PD (India)

Denmark vs India (NG)

Denmark vs India (PD)

Age (years)

51(12)

64(12)

48(13)

51(14)

2.18E−17

2.7E01

4.04E−03

3.00E−20

Gender

F = 90

F = 55

F = 74

F = 68

M = 48

M = 66

M = 63

M = 73

    

Height (cm)

170(15)

172(14)

159.4(14.7)

162.4(14.2)

9.50E01

3.4E01

1.13E−16

2.74E−13

Weight (kg)

79.1(15.3)

82.2(19.6)

67.3(21)

70(15.3)

7.79E02

8.6E02

1.54E−09

3.50E−10

Waist to hip ratio

0.89(0.135)

0.94(0.1)

0.89(0.11)

0.91(0.12)

6.62E−06

1.9E01

3.09E01

9.18E−03

BP systolic (mmHg)

128(23.8)

137(25)

120(24)

122(24)

8.03E−04

6.8E01

3.16E−04

4.53E−11

BP diastolic (mmHg)

80(14)

83(15)

78(14)

79(12)

8.47E02

5.5E01

2.22E−04

9.18E−03

Glucose (mmol/L)

5.3(0.6)

6.2(0.5)

5(0.4)

5.8(0.6)

9.17E−33

2.2E−27

1.22E−08

2.56E−14

(mg/dL)

95.4(10.8)

111.6(9.0)

90(7.2)

104.4(10.8)

    

HbA1c (DCCT%)

5.2(0.3)

5.8(0.2)

5.5(0.5)

5.7(0.6)

9.50E−35

6.7E−11

2.06E−10

6.61E01

(mmol/mol)

33(3.3)

40(2.2)

37(5.5)

39(6.6)

    

hsCRP (mg/L)

1.76(1.92)

2.08(2.84)

2.7(4.8)

2.8(5.1)

2.26E01

5.6E01

7.09E−05

1.74E−03

IL1β (pg/mL)

0.66(0.97)

0.87(0.74)

1.04(0.8)

1.07(0.9)

2.26E01

5.6E01

2.61E−04

2.70E−03

IL10 (pg/mL)

6.13(8.96)

5.18(7.54)

5.12(5.9)

5.19(5.8)

3.96E01

7.3E01

5.92E02

8.80E01

IL13 (pg/mL)

2.21(6.09)

2.70(6.07)

1.30(1.4)

1.39(2.0)

4.68E01

5.6E01

8.54E−06

1.36E−04

IL17A (pg/mL)

7.12(8.58)

5.90(6.23)

4.64(5.9)

5.09(5.7)

2.01E01

5.6E01

8.50E−05

1.55E01

IL23 (pg/mL)

162.68(225.2)

190.40(174.6)

200.7(259.2)

213.3(290.1)

4.68E01

9.7E01

5.92E02

3.40E01

IL6 (pg/mL)

1.45(1.63)

2.08(3.16)

2.26(1.6)

2.32(2.1)

4.67E−04

5.6E01

2.45E−06

2.46E01

MCP1 (pg/mL)

1238.04(666.6)

1378.70(690)

838.8(846.1)

689.6(689.2)

2.26E01

3.8E01

8.71E−09

6.27E−17

TNFα (pg/mL)

2.80(1.66)

3.66(1.84)

5.15(3.3)

5.23(4.3)

1.35E−05

1.0E+ 00

1.51E−19

3.50E−08

LBP (μg/mL)

11.23(6.98)

13.84(7.56)

16.74(8.4)

15.4(8.1)

7.93E−04

5.6E01

3.29E−10

4.69E−02

IAP (μg/mL)

0.32(0.21)

0.37(0.27)

0.35(0.32)

0.36(0.27)

3.91E−02

5.6E01

2.97E01

7.90E01

  1. Abbreviations: BP blood pressure, HbA1c glycated hemoglobin, hsCRP high-sensitive C-reactive protein, IL1β interleukin 1β, IL10 interleukin 10, IL13 interleukin 13, IL17A interleukin 17A, IL23 interleukin 23, IL6 interleukin 6, MCP1 monocyte-chemoattractant protein 1, TNFα tumor necrosis factor α, LBP lipopolysachharide-binding protein, IAP intestinal alkaline phosphatase
  2. Note: The significantly different parameters (Benjamini-Hochberg-corrected padj < 0.05) in the PD group from each cohort are highlighted in bold face fonts