Fig. 4From: Clinical-grade whole-genome sequencing and 3′ transcriptome analysis of colorectal cancer patientsMost frequent single base substitution mutational signatures shown in hierarchical cluster plot (samples with identical signature combinations were collapsed); single-based substitution signatures on the x-axis, samples on the y-axis. Colour heat map correlates to the strength of association with SBS signature (red = strong, blue = weak)Back to article page