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Table 1 Characteristics of the IgG4-RD, SSc, and control cohorts used in the study. Other treatments include mycophenolate mofetil, methotrexate, hydroxychloroquine, abatacept, cyclophosphamide, azathioprine, tocilizumab, and etanercept. RTX rituximab, lcSSc limited cutaneous, dcSSc diffuse cutaneous, ssSSc sine scleroderma, osSSc overlap scleroderma

From: Congruent microbiome signatures in fibrosis-prone autoimmune diseases: IgG4-related disease and systemic sclerosis

 

Controls

IgG4-RD

Systemic sclerosis

N samples

165

58

90

N per subtype

na

Active: 13, inactive: 45

lcSSc: 39, dcSSc: 39, ssSSc: 7, osSSc: 5

Age, years (median ± sd)

57 ± 8

61 ± 13

57 ± 12

Males/females

58/107

29/29

16/74

RTX

0

16

1

Prednisone

0

7

27

Other treatment

0

3

44

Data collection center

Massachusetts General Hospital

Massachusetts General Hospital

University of Michigan