Fig. 6

N. gonorrhoeae genomes carrying genetic AMR mechanisms associated with azithromycin resistance were selected in Pathogenwatch (n = 1142) and combined with genomes from a global collection [65, 112] (total n = 1528) for background contextualization. a Main layout of the combined collection, with an emerging lineage carrying an N. lactamica-like mtr mosaic (‘mtr_mosaic.2’) spanning the mtrR promoter and mtrD marked in red in the tree and the map. b Timeline of the genomes carrying mtr mosaic 2 (in red) and other public genomes in the database without this genetic AMR mechanism. c Visualisation of the mtr mosaic 2-carrying lineage (n = 520) spreading in the USA and Australia (see legend) using Microreact. The arrow in turquoise colour marks the divergence of the Australian lineage, shown in more detail in d coloured by the presence (in red) or absence (in white) of the porB1b G120K and A121N mutations. The Pathogenwatch project of this case study can be explored in [135]. The contents of and boundaries in the map are the sole responsibility of Pathogenwatch and do not necessarily reflect the views or opinions of WHO or other Public Health Agency