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Fig. 6 | Genome Medicine

Fig. 6

From: Molecular features of untreated breast cancer and initial metastatic event inform clinical decision-making and predict outcome: long-term results of ESOPE, a single-arm prospective multicenter study

Fig. 6

Mutational profile of de novo versus late metastases. a Landscape of private versus shared mutations in primary tumors and their matched metastatic tissue, according to metastasis onset pattern. b Pie plot showing the proportion of private versus shared mutations in primary tumors and their matched metastatic tissue. c Box-plot showing the mutation number in late versus de novo metastases. White box: de novo metastases; black box: late metastases. *p < 0.01. d Box-plot showing the median of shared and private driver mutations identified in late and de novo breast cancers. Dark boxes: shared mutations; gray box: private mutations; ***p < 0.0001

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