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Table 2 Overall survival multivariate analysis

From: Molecular features of untreated breast cancer and initial metastatic event inform clinical decision-making and predict outcome: long-term results of ESOPE, a single-arm prospective multicenter study

 

Categories

N

HR

95%CI

P value

Visceral metastases

No

8

1

 

0.01

Yes

52

6.57

[1.17; 36.97]

Metastases molecular subtype

Luminal A

8

1

 

< 0.001

HER2

15

1.29

[0.32; 5.18]

Triple negative

13

10.47

[2.73; 40.17]

Luminal B

24

3.49

[1; 12.19]

Number of metastatic sites

1–2

37

1

 

0.002

3+

23

2.9

[1.5; 5.62]

LAMA2 mutation in metastasis

Wild type

58

1

 

0.043

mutated

2

8.67

[1.43; 52.4]