Fig. 3
From: Microglial PGC-1α protects against ischemic brain injury by suppressing neuroinflammation
PGC-1α enhances microglial ramification and alters gene expression profiles. a Representative images of Imaris-based three-dimensional reconstruction of Iba-1+ microglia from PGC-1αf/f and mPGC-1α mice. b Morphological features, including dendrite length, number of segments, branch points, and terminal points were quantified using Imaris. c A total of 260 upregulated and 232 downregulated genes were identified using microarray analysis of microglia. d GO analysis showed the top 20 enriched biological processes. **p < 0.01; a, b n = 5 per group, c, d n = 3 per group