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Fig. 6 | Genome Medicine

Fig. 6

From: Finding associations in a heterogeneous setting: statistical test for aberration enrichment

Fig. 6

Results under less heterogeneity, i.e. higher values of r.a Ability of the different tests to detect the association for higher values of r. A method is able to detect the signal if the p value is lower than the threshold in the majority of 200 reruns. Here we show the results for d=3. We compare our test (O), the Levene test (L), t-test (T), and Wilcoxon (W) test. b Comparison of the p value magnitude between our test and the best out oft-test, Levene test, and Wilcoxon test, depending on simulations parameters n (sample size) and r (proportion of affected cases). Here we show the results for d=3. The colors indicate the difference in log10 between the p values returned by both method. For example b indicates that our test’s p value is two orders of magnitude (100 times) smaller than that of the Levine test. We capped the maximal difference at 4 for visual clarity

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