Table 3 NBD risk genes identified in GWAS

AD

ABCA7, ACE, ADAM10, ADAMTS1, APOE, BIN1, BCKDK, CASS4, CD2AP, CD33, CELF1, CLU, CR1, DSG2, EPHA1, FERMT2, HLA-DRB1, HLA-DRB5, INPP5D, IQCK, KAT8CR1, MEF2C, MS4A6A, NME8, PICALM, PTK2B, SLC24A4, SORL1, WWOX, ZCWPW1

[24,25,26,27,28,29,30]

PD

ACMSD, ASXL3, BCKDK, BRIP1, BST1, C5orf24, CAB39L, CCDC62, CD19, CHRNB1, CLCN3, CRLS1, DDRGK1, DGKQ, DNAH17, DYRK1A, FAM171A2, FAM47E, FAM49B, FBRSL1, FCGR2A, FGF20, FYN, GAK, GBA, GBF1, GPNMB, HIP1, HLA-DQB1, HLA-DRA, HLA-DRB5, INPP5F, KCNIP3, KCNS3, KPNA1, LAMP, LCORL, LINC00693, MAPT, MBNL2, MCCC1/3, MED12L, MEX3C, MIPOL1, NOD2, NUCKS, PAM, RAB29, RAB7L1, RAI1, RIMS1, RIT2, RNF141, RPS12, RPS6KL1, SCAF11, SCARB2, SIPA1L2, SNCA, SPTSSB, SREBF1, STBD1, STK39,STX1B, SYT11, TMEM163, TMEM175, TRIM40, UBAP2, UBTF, VAMP4, VPS13C

[22, 31,32,33]

FTD

BTNL2, C4orf27, CTSC, DPP6, HLA-DRA, HLA-DRB5, HLA-DQA2, IMMP2L, IRF2, MIR548AP, OLFM1, RAB38, RERG, TMEM106B, UNC13A

[21, 34]

ALS

C21orf2, DPP6, FGGY, ITPR2, KIF5A, MOBP, SARM, SCFD1, UNC13A

[23, 35, 36]