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Table 3 NBD risk genes identified in GWAS

From: Emerging genetic complexity and rare genetic variants in neurodegenerative brain diseases

NBD Risk genes References
AD ABCA7, ACE, ADAM10, ADAMTS1, APOE, BIN1, BCKDK, CASS4, CD2AP, CD33, CELF1, CLU, CR1, DSG2, EPHA1, FERMT2, HLA-DRB1, HLA-DRB5, INPP5D, IQCK, KAT8CR1, MEF2C, MS4A6A, NME8, PICALM, PTK2B, SLC24A4, SORL1, WWOX, ZCWPW1 [24,25,26,27,28,29,30]
PD ACMSD, ASXL3, BCKDK, BRIP1, BST1, C5orf24, CAB39L, CCDC62, CD19, CHRNB1, CLCN3, CRLS1, DDRGK1, DGKQ, DNAH17, DYRK1A, FAM171A2, FAM47E, FAM49B, FBRSL1, FCGR2A, FGF20, FYN, GAK, GBA, GBF1, GPNMB, HIP1, HLA-DQB1, HLA-DRA, HLA-DRB5, INPP5F, KCNIP3, KCNS3, KPNA1, LAMP, LCORL, LINC00693, MAPT, MBNL2, MCCC1/3, MED12L, MEX3C, MIPOL1, NOD2, NUCKS, PAM, RAB29, RAB7L1, RAI1, RIMS1, RIT2, RNF141, RPS12, RPS6KL1, SCAF11, SCARB2, SIPA1L2, SNCA, SPTSSB, SREBF1, STBD1, STK39,STX1B, SYT11, TMEM163, TMEM175, TRIM40, UBAP2, UBTF, VAMP4, VPS13C [22, 31,32,33]
FTD BTNL2, C4orf27, CTSC, DPP6, HLA-DRA, HLA-DRB5, HLA-DQA2, IMMP2L, IRF2, MIR548AP, OLFM1, RAB38, RERG, TMEM106B, UNC13A [21, 34]
ALS C21orf2, DPP6, FGGY, ITPR2, KIF5A, MOBP, SARM, SCFD1, UNC13A [23, 35, 36]