Skip to main content

Table 2 Observed SARS-CoV-2 mutations in clinical samples

From: Profiling SARS-CoV-2 mutation fingerprints that range from the viral pangenome to individual infection quasispecies

Mutation Gene / open reading frame Translational change Sample frequency
(n = 30)
Samples GISAID frequency
n = 75,681)
2721 C>T Nsp3 A1V 1 P145 7
3037 C>T Nsp3 Synonymous 5 P133, P152, P128, P140,
P125
62,018
7482 C>T Nsp3 S1588L 1 P162 10
8092 C>T Nsp3 Synonymous 1 P145 42
8389 C>T Nsp3 Synonymous 1 P133 154
11074 CT>C NA Microsatellite 3 P155, P128, P142 NA
16267 C>A Helicase Q11K 1 ATCC_WA-01 NA
16375 C>T Helicase P47S 1 P142 16
16876 A>G Helicase T214A 1 P132 0
17747 C>T Helicase P504L 1 P145 2104
17858 A>G Helicase Y541C 1 P145 2167
18060 C>T 3′ to 5′ exonuclease Synonymous 2 ATCC_WA-01, P145 2233
18084 C>T 3′ to 5′ exonuclease Synonymous 1 P126 4
21646 C>T S Synonymous 1 P151 257
22289 G>T S A243S 1 P152 15
23403 A>G S D614G 3 P152, P125, P133 61,993
26542 C>T M T7I 1 ATCC_WA-01 13
26625 C>T M Synonymous 1 P144 86
26951 G>T M Synonymous 1 P146 44
27131 C>T M Synonymous 1 P137 16
27641 C>T ORF7a S83L 1 P126 31
27670 G>T ORF7a V93F 1 P139 35
27874 C>T ORF7b T40I 2 P144, P146 40
27925 C>T ORF8 T11I 1 P138 22
27970 C>T ORF8 T26I 1 P132 66
28144 T>C ORF8 L84S 2 P145, ATCC_WA-01 4655