Fig. 4
From: Single-cell sequencing of the small and AT-skewed genome of malaria parasites
Correlations show reproducibility of amplification pattern by optimized MALBAC. a Paired panels for 5 × 5 matrices represent Spearman correlation, histogram, and pairwise scatterplot among the normalized read abundance of the Dd2 bulk, ENM, LNM, and one of each EOM and LOM samples. Outlier bins were removed prior to this analysis (see “Methods” for outlier identification). The Spearman correlation coefficients of each pair are listed above the diagonal, and stars indicate the p value at levels of 0.1 (no star), 0.05 (*), 0.01 (**), and 0.001 (***). The histograms on the diagonal show the distribution of normalized read abundance in each sample. The bivariate scatter plots, below the diagonal, depict the fitted line through locally smoothed regression and correlation ellipses (an ellipse around the mean with the axis length reflecting one standard deviation of the x and y variables). b Spearman correlation coefficients between sequenced samples. The hierarchical clustering heatmap was generated using Spearman correlation coefficients of normalized read abundance. The color scale indicates the degree of correlation (white, correlation = 0; green, correlation > 0)