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Fig. 7 | Genome Medicine

Fig. 7

From: Phylogroup stability contrasts with high within sequence type complex dynamics of Escherichia coli bloodstream infection isolates over a 12-year period

Fig. 7

Schematic representation of the different scenarios leading to within STc dynamic. a Example of clonal replacement as observed in STc95. The represented plasmid corresponds to pS88 whereas the red terminal branches correspond to the emerging O1:H7 fimH41 subgroup A clone. The emerging O25b:H4 clone in the subgroup D is indicated by colored squares as in Fig. 3 and the branches are highlighted in green. b Multiple acquisitions of related PAIs associated to clonal expansion as observed in STc69 and STc131. The pap gene cluster with the papGII allele is represented in red on genetic maps. Red arrows indicate the acquisition of PAIs. c High antigenic diversity at a given time and overtime, as observed in STc10. This pattern corresponds probably to multiple recombination events at the main chromosomal hot spots (rfb, fimH)

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