Fig. 2

Sensitivity of the four single liquid biopsy analytes and Kaplan–Meier curves of the individual parameters. a Sensitivity defined by the prevalence of patients (in total n=26) with at least one variant (cfDNA or CTC gDNA) or one overexpression signal (CTC mRNA or EV mRNA). b The number of variants or overexpression signals per patient in each individual analyte was compared. The mean and standard deviation were indicated as solid lines and whiskers, respectively. c–f Data of patients with at least one variant/signal are depicted in red. Only significant correlations [calculated by log-rank (Mantel–Cox) test (p-value ≤ 0.05)] are shown. cfDNA variants in three genes (c, e, f) and MUC16 variants in CTCs (d) showed a significant correlation with OS