Fig. 5
From: Integrative statistical analyses of multiple liquid biopsy analytes in metastatic breast cancer
Mutual information (b) illustrated by an area-proportional Euler diagram (a) and singular value decomposition (c). a, b Pairwise comparison revealed the greatest overlap between information contained in CTC gDNA with the information contained in the other three analytes (threshold >0.8). The mutual information values were found to be rather low. Each analyte therefore added information that was absent in the other analytes. c The steps to identify the 15 strongest singular vectors representing parameters of all four analytes. Singular value decomposition of the input matrix resulted in an adjunct matrix of singular vectors. Normalization and sorting according to magnitude revealed that the 15 strongest singular vectors originated from all four analytes