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Fig. 1 | Genome Medicine

Fig. 1

From: Single-cell characterization of macrophages in glioblastoma reveals MARCO as a mesenchymal pro-tumor marker

Fig. 1

Identification via scRNA-seq of a MARCO+ subpopulation of macrophages specific to IDH1-WT glioblastoma. a Single-cell depiction of 79,968 glioblastoma cells reveals a macrophage population characterized by CD14. b Applying gene filtering and unsupervised clustering upon these macrophages reveals MARCO as defining an anti-inflammatory side opposite to CCL4. c Single-cell exploration of 18,047 lower-grade glioma cells reveals little MARCO expression within the macrophage population (d). e The mean MARCO expression among macrophages is specific to IDH1-wild-type GBM (above), while the mean CD14 expression among macrophages is similar (below)

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Genome Medicine

ISSN: 1756-994X

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