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Table 1 Demographics of the study population

From: The host transcriptional response to Candidemia is dominated by neutrophil activation and heme biosynthesis and supports novel diagnostic approaches

 

Bacterial, Viral, & SIRS

Candidemia

P value*

Discovery (n=100)

Validation (n=21)

Discovery (n=23)

Validation (n=25)

Mean age (years) ± SD

54.0 ± 20.8

43.4 ± 21.3

54.1 ± 17.2

51.8 ± 16.9

0.93

Solid organ transplant

4 (4)

0 (0)

5 (22)**

8 (32)

0.0002

 Liver

0 (0)

 

1 (14)

1 (13)

 

 Heart

0 (0)

 

1 (14)

2 (25)

 

 Lung

1 (25)

 

4 (57)

4 (50)

 

 Kidney

3 (75)

 

1 (14)

1 (13)

 

Cancer diagnosis

9 (9)

1 (5)

4 (17)

8 (34)

0.04

ICU

18 (18)

6 (27)

11 (48)

6 (26)

0.34

HIV

1 (1)

0 (0)

1 (4)

0 (0)

0.67

30-day mortality

6 (6)

1 (5)

4 (17)

3 (12)

0.23

Mean QSOFA ± SD

1.03 ± 0.93

1.00 ± 1.00

0.75 ± 0.77

0.52 ± 0.67

0.03

  1. Values are presented as n (%) unless otherwise specified
  2. SD standard deviation, ICU intensive care unit, HIV human immunodeficiency virus, QSOFA Quick Sequential Organ Failure Assessment
  3. Full demographics were not available on all subjects
  4. *Significance defined as p<0.05 for all candidemia vs. all other groups
  5. **7 organ transplants on 5 subjects