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Fig. 2 | Genome Medicine

Fig. 2

From: Prediction of combination therapies based on topological modeling of the immune signaling network in multiple sclerosis

Fig. 2

Phosphoproteomic measurement and normalization pipeline. a xMAP mean fluorescence intensity (MFI) log values of the 17 analyzed phosphoproteins, b fold change distribution, c non-linearly normalized values (see the “Methods” section). Orange measurements a–c: values of the same patient to allow visualization of the changes across data transformation. d Percentage of patients, for which each phosphoprotein was classified as phosphorylated, dephosphorylated, or non-significant after statistical testing

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Genome Medicine

ISSN: 1756-994X

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