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Fig. 3 | Genome Medicine

Fig. 3

From: A global overview of genetically interpretable multimorbidities among common diseases in the UK Biobank

Fig. 3

Characteristics of the genetic components shared by multimorbidities. a The ratios of SNPs located in genic region, intergenic region, and noncoding RNA region for multimorbidity SNPs, other disease SNPs, and non-disease SNPs. b CADD score distributions for multimorbidity SNPs, other disease SNPs, and non-disease SNPs. c Overlaps between multimorbidity genes and essential genes, and between disease genes and essential genes. d The pLI distributions of multimorbidity genes, other disease genes, and non-disease genes. e The ratios of genes expressed in certain numbers of tissues, for multimorbidity genes, other disease genes, and non-disease genes. f Top ten pathways that are shared by the largest numbers of multimorbidities

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Genome Medicine

ISSN: 1756-994X

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