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Fig. 5 | Genome Medicine

Fig. 5

From: The DNA methylation landscape of multiple myeloma shows extensive inter- and intrapatient heterogeneity that fuels transcriptomic variability

Fig. 5

Intermediate methylation level of CGIs in PC-PMDs. a Mean DNA methylation level at diagnosis in promoter, CGIs, shores, and shelves regions according to the presence or absence of PC-PMDs. b Proportion of CGIs according to their methylation levels inside and outside PC-PMDs: horizontal bars represent individual samples (MM at the top and NPC at the bottom). c Example of a locus with the same average level of DNA methylation and radically different PDR values. d Proportion of loci with more than 50% discordant reads inside and outside PC-PMDs

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