Fig. 2
From: Recombination and lineage-specific mutations linked to the emergence of SARS-CoV-2
Recombination analysis in MERS coronaviruses. a Distribution of 24 recombination events among human and non-human MERS-CoV isolates. The spike protein and its RBD are highlighted. b Sliding window analysis shows (blue curve) the distribution of recombination breakpoints (either start or end) in 800 nucleotide (nt) length windows upstream (namely, in the 5′ to 3′ direction) of every nt position along the viral genome. The spike protein, and the RBD in particular, overlap with widows that are enriched in recombination breakpoints. Binomial test p values (red curve) and the 5% significance level are shown (dotted line). The MERS-CoV membrane protein is highlighted (dark gray); it also shows an enrichment of recombination breakpoints