Skip to main content
Fig. 1 | Genome Medicine

Fig. 1

From: Transfer learning between preclinical models and human tumors identifies a conserved NK cell activation signature in anti-CTLA-4 responsive tumors

Fig. 1

Graphical summary. Visual summary of the computational workflow, data types (scRNA-seq, CyTOF, or bulk RNA-seq), and sources (preclinical or clinical) used to identify conserved responses to immunotherapy. In response to anti-CTLA-4 therapy, we detect natural killer cell activation in mice and human tumors and demonstrate that human natural killer cells express CTLA-4 and bind anti-CTLA-4 at the cell surface

Back to article page

Genome Medicine

ISSN: 1756-994X

Contact us