Fig. 4

DNA methylation and RNA expression in MCC cell lines. A Unsupervised clustering of probes based on MCC-specific DNA methylation compared to MS1 and MCC13 cell lines. B Differentially methylated genes in the four clusters were overlapped with MS1 and MCC13. Percentage of genes showing DNA methylation similar to cell lines were recorded. C Volcano plot for gene expression by RNA-seq in MS1 and MCC13 cell lines compared to normal skin samples