Drug name | Phenotype | GenTB - RF | GenTB - WDNN | Mykrobe | TB-Profiler | |||||
---|---|---|---|---|---|---|---|---|---|---|
 | R (n) | S (n) | Sensitivity (95% CI) | Specificity (95% CI) | Sensitivity (95% CI) | Specificity (95% CI) | Sensitivity (95% CI) | Specificity (95% CI) | Sensitivity (95% CI) | Specificity (95% CI) |
Isoniazid | 6,043 | 13,112 | 91% (91 to 92) | 98% (97 to 98) | 90% (89 to 91) | 99% (99 to 99) | 87% (86 to 88) | 98% (98 to 98) | 91% (90 to 92) | 98% (97 to 98) |
Rifampicin | 5,068 | 14,474 | 93% (93 to 94) | 98% (98 to 98) | 88% (88 to 89) | 99% (99 to 99) | 90% (89 to 91) | 98% (98 to 99) | 92% (91 to 93) | 98% (98 to 99) |
Ethambutol | 2,936 | 12,362 | 86% (85 to 87) | 92% (92 to 93) | 82% (80 to 83) | 93% (93 to 94) | 79% (77 to 80) | 93% (93 to 94) | 86% (85 to 88) | 92% (92 to 93) |
Pyrazinamide | 508 | 1,544 | 79% (76 to 83) | 94% (93 to 95) | 80% (79 to 82) | 95% (94 to 95) | 72% (71 to 74) | 98% (97 to 98) | 83% (80 to 86) | 96% (96 to 97) |
Amikacin | 618 | 3,458 | 67% (63 to 71) | 99% (99 to 100) | 66% (62 to 70) | 99% (99 to 100) | 63% (60 to 67) | 99% (99 to 100) | 55% (51 to 59) | 99% (99 to 100) |
Capreomycin | 648 | 3,733 | 63% (59 to 67) | 97% (97 to 98) | 57% (53 to 61) | 98% (98 to 99) | 60% (56 to 64) | 98% (98 to 99) | 56% (52 to 60) | 96% (95 to 96) |
Ethionamide | 502 | 1,094 | 67% (63 to 72) | 78% (75 to 80) | - | - | - | - | 70% (66 to 74) | 73% (70 to 76) |
Kanamycin | 576 | 3,707 | 68% (64 to 72) | 99% (98 to 99) | 66% (62 to 70) | 100% (99 to 100) | 66% (63 to 70) | 99 (99 to 100) | 68% (64 to 71) | 98% (98 to 99) |
Streptomycin | 2,126 | 4,968 | 82% (80 to 83) | 89% (88 to 90) | 87% (85 to 88) | 87% (86 to 88) | 68% (66 to 70) | 95% (95 to 96) | 71% (70 to 73) | 95% (95 to 96%) |
Ofloxacin | 743 | 4,038 | 68% (65 to 72) | 99% (98 to 99) | 62% (58 to 66) | 96% (95 to 96) | 62% (58 to 65) | 99% (98 to 99) | 67% (63 to 70) | 98 (98 to 99) |