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Table 2 Area under the receiver operating characteristic curve for GenTB-RF and GenTB-WDNN

From: GenTB: A user-friendly genome-based predictor for tuberculosis resistance powered by machine learning

Drug

GenTB-RF

GenTB-WDNN

 

Area under the ROC curve (95% CI)

Isoniazid

0.94 (0.94 to 0.95)

0.94 (0.94 to 0.95)

Rifampicin

0.96 (0.95 to 0.96)

0.94 (0.93 to 0.94)

Ethambutol

0.89 (0.88 to 0.9)

0.87 (0.87 to 0.87)

Pyrazinamide

0.90 (0.88 to 91)

0.88 (0.87 to 0.88)

Amikacin

0.83 (0.81 to 0.85)

0.83 (0.81 to 0.84)

Capreomycin

0.80 (0.78 to 0.82)

0.78 (0.76 to 0.80)

Ethionamide

0.73 (0.7 to 0.75)

-

Kanamycin

0.83 (0.81 to 0.85)

0.83 (0.81 to 0.85)

Streptomycin

0.85 (0.84 to 0.86)

0.87 (0.86 to 0.88)

Ofloxacin

0.83 (0.82 to 0.85)

0.79 (0.77 to 0.81)

  1. RF = random forest, WDNN = wide and deep neural network