Fig. 1From: Profiling diverse sequence tandem repeats in colorectal cancer reveals co-occurrence of microsatellite and chromosomal instability involving Chromosome 8An integrated sequencing-based determination of microsatellite and chromosomal instabilities. An overview of the sequencing analysis that simultaneously determines microsatellite instability (MSI) and chromosomal instability (CIN) is shown. Mutations in driver genes also provide supplementary information that further supports the integrated determination. Shown here is an example of a BRAF V600E mutation detected from an MSI tumorBack to article page