Fig. 4From: Profiling diverse sequence tandem repeats in colorectal cancer reveals co-occurrence of microsatellite and chromosomal instability involving Chromosome 8Mutation profile for genes related to DNA maintenance. a Oncoplot for the DNA maintenance genes. For all of the genes related to DNA maintenance (rows), mutation profiles of 46 tumors (columns) are shown. Only the mutations with a CADD score greater than 20 are used. Different types of somatic mutations are shown as rectangles with different colors. Gray color indicates that there is no mutation call at a given gene. Germline mutations are also indicated with a shorter rectangle overlaid on the somatic mutation map. The right panel shows the number of affected samples for each gene. Genes are sorted according to the frequency of somatic mutations. The lower panel indicates MSI and CIN sample annotations determined by the sequencing assay. b Distribution of alternative allelic fractions in the P592 tumor. The mutations with an allelic fraction less than 0.1 are indicated with red color, and the percentage is also provided on top of the corresponding histogram barsBack to article page