Fig. 2From: Bacteroides vulgatus and Bacteroides dorei predict immune-related adverse events in immune checkpoint blockade treatment of metastatic melanomaToxicity-free survival using GMB clusters. A Kaplan-Meier curve is shown for the survival to 1st grade 2 (or higher) toxicity event. The GMB2 GMB cluster is shown in blue, and the GMB1 GMB cluster is shown in orange. B A forest plot showing the results of the proportional hazards regression model analysis with the GMB clusters serving as the predictor with adjustment for the subject age, sex, BMI, and ICB treatment. The results indicate a significantly higher risk of suffering a grade 2 toxicity even based on belonging to the GMB1 cluster; HR = 6.88 [95% CI: 1.33–35.58], p = 0.021Back to article page