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Fig. 4 | Genome Medicine

Fig. 4

From: Bacteroides vulgatus and Bacteroides dorei predict immune-related adverse events in immune checkpoint blockade treatment of metastatic melanoma

Fig. 4

Volcano plot showing differentially abundant genes between the GMB risk clusters. Volcano plot shows the top 25% of most variant genes in terms of RPK. Genes were stratified by the microbial strain of origin when a confident identification could be made using HUMAnN 2.0. Genes were considered to be significantly differentially abundant when the FDR < 0.05 and the log2FC > 2.0. The x-axis in the plot indicates which GMB cluster the genes were elevated (left for GMB2 and right for GMB1). The y-axis shows the log of the significance level. The results show that 22,985/40,749 were significantly elevated within the GMB1 cluster and only 17,764/40,749 within the GMB2 cluster

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Genome Medicine

ISSN: 1756-994X

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