Fig. 1

Study groups and analyses. Analysis 1: Comparisons of 103 women immediately prior to excisional treatment versus 39 healthy, untreated controls with normal cytology. Analysis 2: Comparisons of 103 paired samples of women immediately prior to excisional treatment versus 6 months after. Analysis 3: Comparisons of 103 treated women at 6-month follow-up versus 39 healthy, untreated controls with normal cytology. Subgroup analysis 3A: Comparison on 81 treated women with normal cytology at follow-up versus 39 healthy, untreated controls with normal cytology. Subgroup analysis 3B: Comparison of 70 treated women with negative cytology and HPV test versus 23 healthy, untreated controls with negative cytology and HPV test. BNC, borderline nuclear changes; HSIL high-grade squamous intraepithelial lesion; HPV, human papillomavirus