Fig. 7From: The vaginal microbiota and innate immunity after local excisional treatment for cervical intraepithelial neoplasiaCorrelation between bacterial species, antimicrobial peptides and cytokines before (A) and after (B) treatment in 56 treated women who subsequently had normal cytology, HPV negative at 6-month follow-up (Pearson correlation coefficient). Anaerobes such as Prevotella bivia (p = 0.02, Pearson’s correlation coefficient), Atopobium vaginae (p = 0.005, Pearson’s correlation coefficient), BVAB2 (p < 0.001, Pearson’s correlation coefficient), Streptomyces sp. (p < 0.001, Pearson’s correlation coefficient), and Gemella asaccharolytic (p < 0.001, Pearson’s correlation coefficient) were positively correlated with AMP expression prior to treatment, all of which were also positively correlated with expression of IL-1β (p < 0.001, Pearson’s correlation coefficient). After treatment, there is no significant change in bacterial composition, but AMP expression is no longer correlated with these bacterial speciesBack to article page