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Fig. 3 | Genome Medicine

Fig. 3

From: Combinatorial patterns of gene expression changes contribute to variable expressivity of the developmental delay-associated 16p12.1 deletion

Fig. 3

Differential expression of genes between offspring and carrier and noncarrier parents. A Boxplot shows the proportion of differentially expressed genes in carrier offspring of 13 trios (Additional file 2: Table S1) that were either unique to the offspring or shared with their carrier or noncarrier parents (*p < 0.05, two-tailed paired Mann-Whitney test). Boxplot indicates median (center line), 25th and 75th percentiles (bounds of box), and minimum and maximum (whiskers). B Table shows observed clinical features in eight carrier children with overt developmental phenotypes, as well as enrichments (FDR < 0.05) of differentially expressed genes in each carrier child for biological functions related to each clinical feature. Cells are colored according to the family-specific patterns (uniquely observed or shared with a parent) of differentially expressed genes for each enriched biological process

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Genome Medicine

ISSN: 1756-994X

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