Fig. 6

Effect of natural mutations on neutralizing activity of convalescent plasma. a Neutralization potency of nine convalescent plasma against pseudotyped variants. The data are presented as the highest plasma dilution giving a ≥ 50% inhibition of pseudotyped virus infection (NT50). NT50 values were calculated from three independent experiments. b The neutralizing antiserum titer against pseudotyped RBD variants decreases relative to wildtype pseudotyped virus. Neutralization fold change was calculated as follows: NT50 of the wildtype/NT50 of pseudotyped variants. The data represent one representative experiment of two independent experiments