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Fig. 6 | Genome Medicine

Fig. 6

From: Comprehensive mapping of binding hot spots of SARS-CoV-2 RBD-specific neutralizing antibodies for tracking immune escape variants

Fig. 6

Effect of natural mutations on neutralizing activity of convalescent plasma. a Neutralization potency of nine convalescent plasma against pseudotyped variants. The data are presented as the highest plasma dilution giving a ≥ 50% inhibition of pseudotyped virus infection (NT50). NT50 values were calculated from three independent experiments. b The neutralizing antiserum titer against pseudotyped RBD variants decreases relative to wildtype pseudotyped virus. Neutralization fold change was calculated as follows: NT50 of the wildtype/NT50 of pseudotyped variants. The data represent one representative experiment of two independent experiments

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