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Table 4 Mycological tests and clinical characteristics of patients with at least one result suggestive of invasive pulmonary Aspergillosis

From: Evaluating the potential for respiratory metagenomics to improve treatment of secondary infection and detection of nosocomial transmission on expanded COVID-19 intensive care units

Patient A. fumigatus detection in respiratory samples Galactomannan (positive/tested) AspICU – Putative Criteria [34] ECMO
Sample numbera CMg qPCR (Cq) Culture (Positive/Tested) BAL > 1.0 Serum > 0.5 Radiology Clinical Host
563 S28 Positive 31 Positive    Yes Yes Yes – steroid No
Other ND ND 3/6 0/1 0/0
613 S18 Negative > 40 Negative    Yes Yes No No
Other ND ND 2/2 1/1 0/0
677 S63 Negative > 40 Negative    Yes Yes Yes – steroid No
S54 Negative > 40 Negative   
S52 Negative > 40 Negative   
Other ND ND 0/8 2/2 0/5
740 S59 Negative > 40 Negative    Yes Yes Yes – leukaemia on chemotherapy No
S30 Negative > 40 Negative   
Other ND ND 0/16 1/4 1/2
1033 S8 Positive 33 Positive    Yes Yes Yes – steroid Yes
Other ND ND 0/0 1/1 1/1
1346 S56 Positive 32 Positive    Yes Yes Yes – steroid, anakinra Yes
Other ND ND 0/3 1/1 0/2
1440 S33 Negative > 40 Negative    Yes Yes Yes – steroid, anakinra Yes
Other ND ND 0/4 1/2 0/1
1457 S65 Negative > 40 Negative    Yes Yes Yes – steroid Yes
S64 Negative > 40 Negative   
Other ND ND 0/9 2/2 0/2
1538 S55 Positive 31 Negative    Yes Yes Yes – lymphoma on chemotherapy No
Other ND ND 4/5 0/0 1/1
  1. ND = not done
  2. aOther sample represents samples from the nine patients, retrieved after an ITU episode but were outside the CMg period and were not processed with CMg