Fig. 2From: The genetic case for cardiorespiratory fitness as a clinical vital sign and the routine prescription of physical activity in healthcareICD-10 diagnosis frequency by CRF and PA level. Frequency in the UKB for the top 10 global causes of death in high-income countries in 2016, as reported by the World Health Organization (WHO, Additional file 1: Table S3). The CRF and PA phenotypes above were controlled for age and socioeconomic status (SES, the Townsend deprivation index)—they are the residuals from a regression on age and SES. For some diseases, e.g. breast cancer, disease trends are only meaningful separated by sex. CAD = ischaemic heart disease; STR = stroke; ALZ = Alzheimer’s disease and other dementias; LCX = trachea, bronchus and lung cancers; COPD = chronic obstructive pulmonary disease; LRTI = lower respiratory tract infections; CCX = colon and rectum cancers; DIA = diabetes mellitus; KID = kidney diseases; BCX = breast cancersBack to article page