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Fig. 6 | Genome Medicine

Fig. 6

From: Germline HLA-B evolutionary divergence influences the efficacy of immune checkpoint blockade therapy in gastrointestinal cancer

Fig. 6

Correlation between HLA-B HED and the expression of immune-related genes. a Heatmap of differentially expressed genes (DEGs) between the low HLA-B HED and high HLA-B HED subgroups in the PUCH cohort. DEGs were obtained from a 395-plex RNA immune oncology (RNA IO) profiling platform. b Volcano plot of DEGs. c Pathway enrichment analysis of DEGs by using the enrichPathway function from the ReactomePA R package

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Genome Medicine

ISSN: 1756-994X

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