Fig. 2
From: Constructing germline research cohorts from the discarded reads of clinical tumor sequences
Germline imputation accuracy from tumor sequences. a Mean imputation accuracy (Pearson correlation; y-axis) across sliding windows of 200 SNPs shown for all variants (gray/black) and filtered variants (INFO > 0.4 and MAF > 1%) (blue/light blue) with alternating shading for chromosomes. b Fraction of variants (y-axis) as a function of minimum imputation accuracy (Pearson correlation; x-axis) for all variants (gray) and filtered variants (blue). c Distribution of imputation accuracy (Pearson correlation) for 2-digit and 4-digit HLA alleles that passed (dark blue) or failed (light blue, ~ 10% of variants) INFO-score filtering