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Fig. 3 | Genome Medicine

Fig. 3

From: Population study of the gut microbiome: associations with diet, lifestyle, and cardiometabolic disease

Fig. 3

Significant microbial and functional associations of blood test and anthropomorphic measurements. a A heatmap depicting the top 50 associations across 13 blood test and anthropomorphic measurements colored by the -log(q value)*sign(coefficient). Significant associations (corrected p<0.05) are indicated by an asterisk. b Network of significant associations between microbial taxa (purple circles) and triglycerides, glucose, and HbA1c (orange circles). The thickness of edge (gray) is defined by the strength of Spearman correlation (r) between the relative abundance of the OTU and each feature; heavier edge weight implies stronger correlation. c Bar plot of the log fold change of the average relative abundance for significant OTUs associated with BMI status of normal weight vs obese participants. A positive fold change corresponds to OTUs with greater abundance in participants of normal weight, and a negative fold change corresponds to those with greater abundance in participants who are obese. d A heatmap depicting the top 15 functional pathway associations predicted from PICRUSt across 13 blood test and anthropomorphic measurements colored by the -log(q value)*sign(coefficient). Significant associations (corrected p<0.05) are indicated by an asterisk

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