Skip to main content
Fig. 2 | Genome Medicine

Fig. 2

From: A lepidic gene signature predicts patient prognosis and sensitivity to immunotherapy in lung adenocarcinoma

Fig. 2

The development of gene signatures for lepidic and solid histological subtypes. A PCA plot clustering histological subtypes based on the expression values of 1000 genes. These genes were obtained by pooling the top 200 most specific genes from each of the five subtypes. B The Spearman correlation coefficient between the t-score profiles for each pair of histological subtypes. C The L/S-scores are higher in lepidic/solid-predominant samples than all other samples in the Zabeck dataset GSE58772 [37]. D The L/S-scores are higher in lepidic/solid-predominant samples than all other samples in the Zhu dataset GSE14814 [38]. The p-values are based on the Wilcoxon rank sum test

Back to article page

Genome Medicine

ISSN: 1756-994X

Contact us